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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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*Includes seizure clusters and acute or prolonged seizures

164 result(s)

phase 2

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Efficacy and Safety of Rozanolixizumab in Moderate to Severe Generalized Myasthenia Gravis: A Phase 2 Randomized Control Trial

Bril Vera, Benatar Michael, Andersen Henning et al.  February 09, 2021
phase 3

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab versus ustekinumab for the treatment of moderate to severe plaque psoriasis (BE VIVID): Efficacy and safety from a 52-week, multicentre, double-blind, active comparator and placebo controlled phase 3 trial.

Reich Kristian, Krueger James, Blauvelt Andrew et al.  February 06, 2021
phase 3

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): A multicentre, double-blind, placebo-controlled, randomised trial.

Gordon B. Kenneth, Foley Peter, Krueger G. James et al.  February 06, 2021
phase 3

NAYZILAM® (midazolam) CIV

Seizure Emergencies

Clinical pharmacokinetic and pharmacodynamic profile of midazolam nasal spray

M René Bouw, Steve S Chung, Barry Gidal et al.  February 03, 2021
phase 3

FINTEPLA® (fenfluramine)

Dravet Syndrome

Fenfluramine hydrochloride provides long-term clinically meaningful reduction in seizure frequency: analysis of an ongoing open-label extension study

Joseph Sullivan, Ingrid E Scheffer, Lieven Lagae et al.  October 19, 2020
phase 2

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F 

Ralph Adams, A. Maroof, Terry Baker et al.  August 21, 2020
phase 2

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab for patients with moderate to severe plaque psoriasis: 60-week results from BE ABLE 2, a randomized, double-blinded, placebo-controlled, phase 2b extension study.

Blauvelt Andrew, Krueger James, Feldman Steven et al.  May 29, 2020
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Effect of lifetime antiepileptic drug treatment history on efficacy and tolerability of adjunctive brivaracetam in adults with focal seizures: post-hoc analysis of a randomized, placebo-controlled trial

Pavel Klein, Richard McLachlan, Kathy Foris et al.  May 25, 2020
phase 2

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

James F Howard Jr, Nowak J Richard, Wolfe I Gil et al.  May 01, 2020
phase 2

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active ankylosing spondylitis: results from a 48-week phase IIb, randomised, double-blind, placebo-controlled, dose-ranging study 

Desiree van der Heijde, Gensler S. Lianne, Deodhar Atul et al.  April 06, 2020