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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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*Includes seizure clusters and acute or prolonged seizures

164 result(s)

phase 3

FINTEPLA® (fenfluramine)

Dravet Syndrome

Long-term safety and effectiveness of fenfluramine in children and adults with Dravet syndrome

Ingrid E Scheffer, Rima Nabbout, Lieven Lagae et al.  March 12, 2025
phase 3

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Long-term safety of cyclical rozanolixizumab in patients with generalized myasthenia gravis: Results from the Phase 3 MycarinG study and an open-label extension

Habib A. Ali, Drużdż Artur, Grosskreutz Julian et al.  March 04, 2025
pre clinical

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Subcutaneous zilucoplan: evaluation of reproductive toxicology

Lemper Marie, C Marc Luetjens, Fuchs Antje et al.  March 04, 2025
phase 3

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Rozanolixizumab in generalized myasthenia gravis: Pooled analysis of the Phase 3 MycarinG study and two open-label extensions

Bril Vera, Drużdż Artur, Grosskreutz Julian et al.  March 04, 2025
pre clinical

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Evaluation of the effect of rozanolixizumab on pregnancy outcomes and pre- and postnatal development in cynomolgus monkeys

Cauvin Annick, Brady Kevin, Cavagnaro Joy et al.  December 19, 2024
phase 1

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Neonatal Fc Receptor Inhibitor Rozanolixizumab: An Ethnic Sensitivity Study in Healthy Japanese, Chinese, and White Participants

Assem El Baghdady, Rocío Lledó-García, Gayfieva Maryam et al.  November 21, 2024
phase 4/RWE

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Usability of the zilucoplan prefilled syringe for the treatment of generalized myasthenia gravis: insights from a human factors validation study

Barbara Domanska, Alessandra Franchini, Boroojerdi Babak et al.  October 15, 2024
pre clinical

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration

Smith Bryan, Kiessling Andrea, Lledo-Garcia Rocio et al.  October 01, 2024
phase 3

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Maintenance of zilucoplan efficacy in patients with generalised myasthenia gravis up to 24 weeks: a model-informed analysis

Guillemette de la Borderie, Chimits Damien, Boroojerdi Babak et al.  September 21, 2024
phase 3

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Efficacy and safety of rozanolixizumab in patients with muscle-specific tyrosine kinase autoantibody-positive generalised myasthenia gravis: a subgroup analysis of the randomised, double-blind, placebo-controlled, adaptive phase III MycarinG study

Habib A. Ali, Sacconi Sabrina, Giovanni Antonini et al.  September 12, 2024