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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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Phase:

*Includes seizure clusters and acute or prolonged seizures

189 result(s)

phase 1

CIMZIA® (certolizumab pegol)

Plaque Psoriasis, Crohn's Disease, Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis, Psoriatic Arthritis

Population PK modeling of certolizumab pegol in pregnant women with chronic inflammatory diseases

Denis Menshykau, Jagdev Sidhu, Laura Shaughnessy et al.  November 01, 2024
phase 4/RWE

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Usability of the zilucoplan prefilled syringe for the treatment of generalized myasthenia gravis: insights from a human factors validation study

Barbara Domanska, Alessandra Franchini, Boroojerdi Babak et al.  October 15, 2024
pre clinical

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration

Smith Bryan, Kiessling Andrea, Lledo-Garcia Rocio et al.  October 01, 2024
phase 3

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Maintenance of zilucoplan efficacy in patients with generalised myasthenia gravis up to 24 weeks: a model-informed analysis

Guillemette de la Borderie, Chimits Damien, Boroojerdi Babak et al.  September 21, 2024
phase 3

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

Efficacy and safety of rozanolixizumab in patients with muscle-specific tyrosine kinase autoantibody-positive generalised myasthenia gravis: a subgroup analysis of the randomised, double-blind, placebo-controlled, adaptive phase III MycarinG study

Habib A. Ali, Sacconi Sabrina, Giovanni Antonini et al.  September 12, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

The Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) scale in patients with axial spondyloarthritis: psychometric properties and clinically meaningful thresholds for interpretation

David Cella, Christine de la Loge, Fatoumata Fofana et al.  August 12, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Comparative Effectiveness of Bimekizumab and Ustekinumab in Patients with Psoriatic Arthritis at 52 Weeks Assessed Using a Matching-Adjusted Indirect Comparison

Philip J Mease, Richard B Warren, Nash Peter et al.  August 09, 2024

CIMZIA® (certolizumab pegol)

Plaque Psoriasis

Certolizumab pegol for the treatment of plaque psoriasis in routine clinical practice: one-year results from the CIMREAL study

Bernhard Korge, Olivier Vanhooteghem, Charles W Lynde et al.  August 01, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Efficacy and Safety of Bimekizumab in Patients With Psoriatic Arthritis With or Without Methotrexate: 52-Week Results From Two Phase 3 Studies

Iain B McInnes, Philip J Mease, Yoshiya Tanaka et al.  July 30, 2024
phase 4/RWE

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Brivaracetam effectiveness and tolerability in older and younger adults with epilepsy: EXPERIENCE, a pooled analysis of international data from retrospective studies

Edward Faught, Hervé Besson, Wendyl D'Souza et al.  July 05, 2024