The Symptoms of gMG Can Vary From Person to Person6,7
Click one of the icons or click the button below to learn more about possible gMG symptoms.
Emotional Impacts6
such as anxiety, fear, and an overarching sense of sadness
Increased forgetfulness or trouble focusing6
Ocular MG4,8,9
often presenting with droopy eyelids and/or double vision, which may progress to gMG in up to 85% of people within two years
Difficulty chewing or speaking6,7
Difficulty swallowing6,7
including choking, vomiting, or food entering your airway, may signal a myasthenic crisis. Seek emergency medical care immediately
Neck Weakness6
becomes easily tired and/or it is painful to hold up the head
Lack of Energy6
tiring more quickly than usual when performing common tasks
Difficulty falling asleep6
or inability to sleep through the night
Difficulty breathing or shortness of breath6,7
including taking quick shallow breaths or struggling to breathe, may be indicative of myasthenic crisis. Seek immediate medical attention
Leg and arm weakness6
including difficulty rising from a seated position
Loss of independence6
such as difficulty getting dressed, completing chores, running errands, driving, and using the bathroom independently
References
ACh, acetylcholine; AChR, acetylcholine receptor; gMG, generalized myasthenia gravis; MG, myasthenia gravis; MuSK, muscle-specific tyrosine kinase; NMJ, neuromuscular junction.
1. Behin A, Le Panse R. J Neuromuscul Dis. 2018;5(3):265-277. 2. Todar K. Todar’s Online Textbook of Bacteriology. University of Wisconsin-Madison. 2002. Accessed Aug 7, 2025. 3. Ludwig RJ, et al. Front Immunol. 2017;8:603. 4. Gilhus NE, Tzartos S, Evoli A, Palace J, Burns TM, Verschuuren J. Nat Rev Dis Primers. 2019;5(1):30. 5. Li Y, Aurora Y, Levin K. Cleve Clin J Med. 2013;80(11):711-721. 6. Jackson K, Parthan A, Lauher-Cherest M, Broderick L, Law N, Barnett C. Neurol Ther. 2023;12(1):107-128. 7. Khadilkar SV, Chaudhari CR, Patil TR, Desai ND, Jagiasi KA, Bhutada AG. Neurol India. 2014;62(5):492-497. 8. Grob D, Brunner N, Namba T, Pagala M. Muscle Nerve. 2008;37(2):141-149. 9. Overview of MG. Myasthenia Gravis Foundation of America. Accessed May 2023. https://myasthenia.org/Professionals/Clinical-Overview-of-MG
US-DA-2500740
References
ACh, acetylcholine; AChR, acetylcholine receptor; gMG, generalized myasthenia gravis; MG, myasthenia gravis; MuSK, muscle-specific tyrosine kinase; NMJ, neuromuscular junction.
1. Behin A, Le Panse R. J Neuromuscul Dis. 2018;5(3):265-277. 2. Todar K. Todar’s Online Textbook of Bacteriology. University of Wisconsin-Madison. 2002. Accessed Aug 7, 2025. 3. Ludwig RJ, et al. Front Immunol. 2017;8:603. 4. Gilhus NE, Tzartos S, Evoli A, Palace J, Burns TM, Verschuuren J. Nat Rev Dis Primers. 2019;5(1):30. 5. Li Y, Aurora Y, Levin K. Cleve Clin J Med. 2013;80(11):711-721. 6. Jackson K, Parthan A, Lauher-Cherest M, Broderick L, Law N, Barnett C. Neurol Ther. 2023;12(1):107-128. 7. Khadilkar SV, Chaudhari CR, Patil TR, Desai ND, Jagiasi KA, Bhutada AG. Neurol India. 2014;62(5):492-497. 8. Grob D, Brunner N, Namba T, Pagala M. Muscle Nerve. 2008;37(2):141-149. 9. Overview of MG. Myasthenia Gravis Foundation of America. Accessed May 2023. https://myasthenia.org/Professionals/Clinical-Overview-of-MG
US-DA-2500740