UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

New Scientific Information: Click the respective link for peer-reviewed, phase 3 publications related to the unapproved uses of bimekizumab for Axial Spondyloarthritis, Psoriatic Arthritis, and Hidradenitis Suppurativa

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phase 4

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab self-injection devices: Two multicenter, randomized, open-label studies on self-administration by patients with psoriasis.

Bagel Jerry, Machala Magdalena, Hellot Scarlett et al. February 2022
phase 2

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Efficacy of bimekizumab and other biologics in moderate to severe plaque psoriasis: A systematic literature review and a network meta-analysis.

Armstrong April, K. Fahrbach, Leonardi Craig et al. July 2022
phase 3

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab versus secukinumab in plaque psoriasis.

Reich Kristian, Warren B. Richard, Lebwohl Mark et al. July 2021
phase 2

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia
 Gravis

Efficacy and Safety of Rozanolixizumab in Moderate to Severe Generalized Myasthenia Gravis: A Phase 2 Randomized Control Trial

Bril Vera, Benatar Michael, Andersen Henning et al. February 2021
phase 3

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): A multicentre, double-blind, placebo-controlled, randomised trial.

Gordon B. Kenneth, Foley Peter, Krueger G. James et al. February 2021
phase 3

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab versus adalimumab in plaque psoriasis.

Warren B. Richard, Blauvelt Andrew, Bagel Jerry et al. July 2021
phase 3

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab versus ustekinumab for the treatment of moderate to severe plaque psoriasis (BE VIVID): Efficacy and safety from a 52-week, multicentre, double-blind, active comparator and placebo controlled phase 3 trial.

Reich Kristian, Krueger James, Blauvelt Andrew et al. February 2021
phase 2

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: efficacy, safety, pharmacokinetics, pharmacodynamics and transcriptomics from a phase IIa, randomized, double-blind multicentre study.

Frick Andrew, J.G. Krueger, Glatt Sophie et al. December 2021
phase 4

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Reduction of anterior uveitis flares in patients with axial spondyloarthritis on certolizumab pegol treatment: final 2-year results from the multicenter phase IV C-VIEW study. 

van der Horst-Bruinsma I, van Bentum R, Verbraak F et al. 2021
phase 2

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia
 Gravis

Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

James F Howard Jr, Nowak J Richard, Wolfe I Gil et al. May 2020
phase 2

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab for patients with moderate to severe plaque psoriasis: 60-week results from BE ABLE 2, a randomized, double-blinded, placebo-controlled, phase 2b extension study.

Blauvelt Andrew, Krueger James, Feldman Steven et al. May 2020