UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.
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phase 3

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Effect of certolizumab pegol over 96 weeks of treatment on inflammation of the spine and sacroiliac joints, as measured by MRI, and the association between clinical and MRI outcomes in patients with axial spondyloarthritis. 

Braun J, Baraliakos X, Hermann et al. 2017
phase 4

CIMZIA® (certolizumab pegol)

Women's Health

Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study. 

Clowse ME, Förger F, Hwang C et al. 2017
phase 3

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Observed incidence rates of uveitis following certolizumab pegol treatment in patients with axial spondyloarthritis. 

Rudwaleit M, Rosenbaum J, Landewe R et al. 2016
phase 4

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study. 

Smolen JS, Burmester GR, Combe B et al. 2016
phase 3

CIMZIA® (certolizumab pegol)

Crohn's Disease

Reinduction with certolizumab pegol in patients with Crohn’s disease experiencing disease exacerbation: 7-year data from the PRECiSE 4 study. 

Lee SD, Rubin DT, Sandborn WJ et al. 2016
phase 4

CIMZIA® (certolizumab pegol)

Crohn's Disease

Safety of long-term treatment with certolizumab pegol in patients with Crohn’s disease, based on a pooled analysis of data from clinical trials. 

Loftus EV Jr, Colombel JF, Schreiber S et al. 2016
phase 3

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial. 

Smolen JS, Emery P, Ferraccioli GF et al. 2015
phase 4

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Update on the safety profile of certolizumab pegol in rheumatoid arthritis: an integrated analysis from clinical trials. 

Bykerk VP, Cush J, Winthrop K et al. 2015
phase 3

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Twenty-eight-week results from the REALISTIC phase IIIb randomized trial: efficacy, safety and predictability of response to certolizumab pegol in a diverse rheumatoid arthritis population. 

Weinblatt ME, Fleischmann R, van Vollenhoven RF et al. 2015
phase 3

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Effect of certolizumab pegol over ninety-six weeks in patients with axial spondyloarthritis. 

Sieper J, Landewe R, Rudwaleit M et al. 2015
phase 3

CIMZIA® (certolizumab pegol)

Psoriatic Arthritis

Effect of certolizumab pegol over 96 weeks in patients with psoriatic arthritis with and without prior antitumor necrosis factor exposure. 

Mease P, Deodhar A, Fleischmann R et al. 2015