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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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*Includes seizure clusters and acute or prolonged seizures

164 result(s)

phase 3

CIMZIA® (certolizumab pegol)

Plaque Psoriasis

Certolizumab pegol for the treatment of chronic plaque psoriasis: Results through 48 weeks of a phase 3, multicenter, randomized, double-blind, etanercept- and placebo-controlled study. 

Lebwohl M, Blauvelt A, Paul C et al.  April 14, 2018
phase 3

CIMZIA® (certolizumab pegol)

Plaque Psoriasis

Certolizumab pegol for the treatment of chronic plaque psoriasis: results through 48 weeks from two phase 3, multicenter, randomized, double-blinded, placebo-controlled studies (CIMPASI-1 and CIMPASI-2). 

Gottlieb A, Blauvelt A, Diamant T et al.  April 13, 2018
phase 2
Plaque Psoriasis

Dual neutralization of both interleukin 17A and interleukin 17F with bimekizumab in patients with psoriasis: Results from BE ABLE 1, a 12-week randomized, double-blinded, placebo-controlled phase 2b trial

K.A. Papp, J. F. Merola, A. B. Gottlieb et al.  March 30, 2018
phase 2

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Dual neutralization of both interleukin 17A and interleukin 17F with bimekizumab in patients with psoriasis: Results from BE ABLE 1, a 12-week randomized, double-blinded, placebo-controlled phase 2b trial.

Krueger James, Feldman Steven, Umezawa Yoshinori et al.  March 30, 2018
phase 3

CIMZIA® (certolizumab pegol)

Psoriatic Arthritis

4-year results from the RAPID-PsA phase 3 randomised placebo-controlled trial of certolizumab pegol in psoriatic arthritis. 

van der Heijde D, Deodhar A, FitzGerald O et al.  March 14, 2018
phase 3

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Limited radiographic progression and sustained reductions in MRI inflammation in patients with axial spondyloarthritis: 4-year imaging outcomes from the RAPID-axSpA phase III randomised trial. 

van der Heijde D, Baraliakos X, Hermann K-G et al.  January 17, 2018
phase 1

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation 

Glatt Sophie, Baeten Dominique, Terry Baker et al.  December 23, 2017
phase 1

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study

Kiessling Peter, Lledo-Garcia Rocio, Watanabe Shikiko et al.  November 01, 2017
phase 4/RWE

CIMZIA® (certolizumab pegol)

Women's Health

Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study. 

Mariette X, Förger F, Abraham B et al.  October 13, 2017
phase 4/RWE

CIMZIA® (certolizumab pegol)

Women's Health

Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study. 

Clowse ME, Förger F, Hwang C et al.  August 16, 2017