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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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*Includes seizure clusters and acute or prolonged seizures

164 result(s)

phase 3

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Effect of certolizumab pegol over 96 weeks of treatment on inflammation of the spine and sacroiliac joints, as measured by MRI, and the association between clinical and MRI outcomes in patients with axial spondyloarthritis. 

Braun J, Baraliakos X, Hermann et al.  April 24, 2017
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Efficacy and tolerability of adjunctive brivaracetam in patients with prior antiepileptic drug exposure: a post-hoc study

Ali A Asadi-Pooya, Michael R Sperling, Steve Chung et al.  February 27, 2017
phase 1

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

First‐in‐human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL‐17A and IL‐17F, in mild psoriasis.

Glatt Sophie, Helmer Eric, Hopson Sari et al.  January 10, 2017
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Time to onset of sustained ≥50% responder status in patients with focal (partial-onset) seizures in three phase 3 studies of adjunctive brivaracetam treatment

Pavel Klein, Martin E Johnson, Jimmy Schiemann et al.  December 18, 2016
phase 4/RWE

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study. 

Smolen JS, Burmester GR, Combe B et al.  November 15, 2016
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Efficacy, safety, and tolerability of adjunctive brivaracetam for secondarily generalized tonic-clonic seizures: pooled results from three phase 3 studies

Brian D Moseley, Michael R Sperling, Ali A Asadi-Pooya et al.  September 03, 2016
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Tolerability, safety, and efficacy of adjunctive brivaracetam for focal seizures in older patients: a pooled analysis from three phase 3 studies

Martin J Brodie, John Whitesides, Jimmy Schiemann et al.  August 18, 2016
phase 3

CIMZIA® (certolizumab pegol)

Crohn's Disease

Reinduction with certolizumab pegol in patients with Crohn’s disease experiencing disease exacerbation: 7-year data from the PRECiSE 4 study. 

Lee SD, Rubin DT, Sandborn WJ et al.  August 01, 2016
phase 4/RWE

CIMZIA® (certolizumab pegol)

Crohn's Disease

Safety of long-term treatment with certolizumab pegol in patients with Crohn’s disease, based on a pooled analysis of data from clinical trials. 

Loftus EV Jr, Colombel JF, Schreiber S et al.  July 25, 2016
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Efficacy and safety of brivaracetam for partial-onset seizures in 3 pooled clinical studies

Elinor Ben-Menachem, Rūta Mameniškienė, Pier Paolo Quarato et al.  June 22, 2016